An international Study of Cardiovascular Disease Prevention, Diabetes and Chronic Kidney Disease in partnership with the World Heart Federation, European Society of Cardiology, Asia Pacific Society of Cardiology, InterAmerican Society of Cardiology and Pan-African Society of Cardiology.
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The objectives of this international
study of 12,000 coronary patients across 30 countries from 5 WHO regions
outside Europe are to (i) describe prevalence of cardiometabolic and
renal risk factors in coronary patients; (ii) describe
current risk factor management to defined targets by
drug therapies (iii) provide an objective assessment of clinical implementation of
international and national guidelines; (iv) investigate the reasons for variation in
preventive cardiology practice between regions and countries; (v) promote
the principles of best preventive cardiology practice
through continental and national societies of cardiology and heart foundations.
INTERASPIRE includes in depth clinical and laboratory
studies of (i) dysglycaemia and diabetes; (ii) chronic kidney disease; (iii)
atrial fibrillation; (iv) familial hypercholesterolaemia; and (v) heart
failure.
This international study is being conducted through
National Societies of Cardiology which have responsibility for appointing
National Coordinators, selecting geographical regions (minimum of three) and
hospital centres (minimum of 6 in each country) together with Principal
Investigators.
The study population is a
consecutive sample of coronary patients from each hospital which meet the
following diagnostic criteria: Acute
coronary syndromes (acute myocardial infarction with ST elevation (STEMI) and
Non ST elevation MI (Non-STEMI) and stable coronary artery disease). Patients
are interviewed and examined in hospital using standardised methodology,
including one central laboratory in Helsinki, Finland, for measurement of
fasting lipids, glucose, HbA1c, creatinine and urinary albumin, and then
followed up for hospitalisations, non-fatal and fatal cardiovascular events and
all cause mortality.
A pilot study in Argentina (8 regions and 8 hospitals) and Malaysia (5 regions and 6 hospitals) is on-going and 400 coronary patient interviews from each country will be completed during 2019 -20; a total of 800 coronary patients.
The main study was launched in 2020, starting with Colombia, followed by China, Indonesia, Japan, Kenya, Nigeria, Philippines, Singapore, Sudan, Tanzania, UAE and USA. With a minimum of 6 hospital centres in each country, we expect 400 coronary patient interviews in 2020-21 (200 in each of the African countries) ; a total of 4000 coronary patients.
The patient data from INTERASPIRE
will be combined with the 8261 coronary patients from 27 countries from the WHO
European region (EUROASPIRE V 2016-18) to give a complete real world picture of
contemporary therapeutic management of cardiometabolic and renal disease and
the impact such care has on event free survival.
INTERASPIRE Co-Principal Investigators:
| Prof David Wood, MB ChB, MSc, FRCP, FRCPE, FFPHM, FESC, FACC, FAHA Adjunct Professor of Preventive Cardiology Director of Science, Strategy and International Relations National Institute for Prevention and Cardiovascular Health National University of Ireland – Galway Emeritus Professor of Cardiology Imperial College London Past President World Heart Federation 2019-20 |
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| John William (Bill) McEvoy, MB BCh BAO, MEd, MHS, FRCPI Professor of Preventive Cardiology, National University of Ireland, Galway Campus. Medical and Research Director, National Institute for Prevention and Cardiovascular Health Consultant Cardiologist, University College Hospital Galway, Saolta Healthcare Group. |
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INTERASPIRE Coordinating Centre, National Institute for Prevention and Cardiovascular Health, National University of Ireland Galway, Ireland
| Agnieszka Adamska MBA, MSc Research Project Manager, National Institute for Prevention and Cardiovascular Health Honorary Clinical Fellow School of Medicine, National University of Ireland, Galway |
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| Dr Catriona Jennings Cardiovascular Specialist Research Nurse Coordinator |
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| Prof Kornelia Kotseva Senior Clinical Research Fellow and Consultant Cardiologist |
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INTERASPIRE Executive Committee
Co-Chairs:
Prof David Wood and Prof John William McEvoy
| Prof Guy G. De Backer, MD, PhD Honorary Professor, Ghent University Faculty of Medicine and Health Sciences Dept Public Health and Primary Care University Hospital Ghent, Dept Cardiology Belgium |
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| Professor Kornelia Kotseva, MD, PhD, FESC Senior Clinical Research Fellow National Institute for Prevention and Cardiovascular Health National University of Ireland – Galway Consultant Cardiologist Imperial College Healthcare NHS Trust, London UK |
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| Dr. Catriona Jennings PhD BA Hons PG Cert ULT RN FESC FPCNA Cardiovascular Specialist Research Nurse Coordinator National Institute for Prevention and Cardiovascular Health National University of Ireland – Galway Discipline of Medicine, Clinical Science Institute, Galway, Ireland |
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| Prof. Dr. Dirk De Bacquer Senior Full Professor of Epidemiology and Biostatistics Head of the Epidemiology & Prevention Unit Head of the Biostatistics Unit Department of Public Health and Primary Care Faculty of Medicine and Health Sciences Ghent University – Belgium |
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| Prof Lars Ryden Senior Professor of Cardiology FoU – Tema Hjärta och Kärl, Karolinska Universitetssjukhuset/Solna Sweden |
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| Prof Gregory Y. H. Lip Price-Evans Chair of Cardiovascular Medicine, University of Liverpool, UK; Distinguished Professor, Aalborg University, Denmark |
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| Prof Kosh Ray Professor of Public Health and Consultant Cardiologist, Imperial College London, UK |
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| Iris Erlund, Research Manager Biochemistry Laboratory Forensic Toxicology Unit Finnish Institute for Health and Welfare (THL), Helsinki, Finland |
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Academic Institutions partnering with INTERASPIRE
Data Managment Centre – EURObservational Research Programme (EORP), European Society of Cardiology, France
Céline Arsac, MSc., PMP – EORP Team Manager
Clara Berlé – Clinical Project Manager
Statistical Centre – Faculty of Medicine and Health Sciences, Ghent University, Belgium
Professor Dirk De Bacquer
Central Laboratory – The National Institute for Health and Welfare (THL), Department of government Services, Forensic Toxicology Unit, Helsinki, Finland
Iris Erlund, Research Manager
Elina Jarvensivu – Interaspire Lead
Diabetes Centre – Cardiology Unit, Department of Medicine Solna, Karolinska Institutet Stockholm, Sweden
Professor Lars Ryden
Participating countries:
Malaysia
National Heart Association of Malaysia
National Heart Association of Malaysia President
Professor Wan Azman Wan Ahmad
FRCP, FAMM, FNHAM, FAPSC, FAsCC, FAPSIC, FSCAI, FACC, FESC, FASc
Senior Consultant Cardiologist
University Malaya Medical Centre, Kuala Lumpur, Malaysia
INTERASPIRE Malaysia National Coordinator
Associate Professor Ahmad Syadi Mahmood Zuhdi
University Malaya Medical Centre, Kuala Lumpur, Malaysia
INTERASPIRE Malaysia Deputy Coordinator
Dr Zainab Abu Kassim
University Malaya Medical Centre, Kuala Lumpur, Malaysia
Malaysia INTERASPIRE Centres
Argentina
Argentine Society of Cardiology
The Argentine Society of Cardiology President
Associate Professor Jose Luis Navarro Estrada, MD, MSc, MTSAC, FACC
Head of Coronary Unit – Hospital Italiano de Buenos Aires, Argentina
Vice Director Department of Research – Hospital Italiano de Buenos Aires
Staff Member, Senior Investigator
Master of Sciences (MSC)(UBA- Harvard)
Associate Professor of Medicine – Instituto Universitario del Hospital Italiano
Full Member of the Argentine Society of Cardiology
The Argentine Society of Cardiology Immediate Past President
Dr Ana M. Salvati, MD, MTSAC, FACC
Chief of Cardiology Service – Clínica Modelo de Morón, Buenos Aires, Argentina
Staff Physician Coronary Unit – Hospital de Clínicas – Universidad de Buenos Aires
INTERASPIRE Argentine National Coordinator
Dr María Inés Sosa Liprandi, MTSAC-FACC
Coordinator Cardiovascular Research, Sanatorio Güemes, Buenos Aires , Argentina
Coordinator Heart Failure Unit, Sanatorio Güemes, Buenos Aires, Argentina
Medical Director, Idea Medica- Research&Education, Buenos Aires, Argentina
Director Cardiomyopathies Council Interamerican Society of Cardiology
INTERASPIRE Argentine Lead
Prof Alvaro Sosa Liprandi
Head of Cardiology, Sanatorio Güemes. Buenos Aires, Argentina
Director, Idea Médica. Research & Education
Director, Post Graduate Medical School in Cardiology, Universidad de Buenos Aires
President Elect. InterAmericanSociety of Cardiology
Argentina INTERASPIRE Centres
Colombia
Colombian Society of Cardiology and Cardiovascular Surgery
CSCCS President
Dr Fernán Del Cristo Mendoza Beltrán
Internal Medicine Specialist: Universidad de Cartagena – Colombia
Specialist in Adult Cardiology: Universidad El Bosque- Colombia
Critical Medicine and Intensive Care Specialist: Universidad de la Sabana – Colombia
Bioethics Specialist: Universidad Javeriana – Colombia
Specialist in Clinical Epidemiology: Universidad El Bosque – Colombia
Specialist in University Teaching: Universidad Militar Nueva Granada – Colombia
Head of the Department of Clinical Cardiology and Internal Medicine: Fundación Clínica Shaio
Head of the Heart Failure and Transplantation Unit: Fundación Clínica Shaio
Associate Professor and Director of the Postgraduate Program in Cardiology: Universidad El Bosque- Colombia
President of the Colombian Society of Cardiology and Cardiovascular Surgery
Fellow American College of Cardiology
CSCCS Immediate Past President :
Prof. Adalberto Quintero-Baiz MD, FACC
Professor of Cardiology at the Faculty of Health Sciences of the Simón Bolívar University
Medical Director, Cardiodiagnostico SA-Barranquilla
Research Subdirector, Bios Foundation
Past President of the Colombian Society of Cardiology and Cardiovascular Surgery
INTERASPIRE Colombia National Coordinator
Dr Miguel Urina Triana MD, Msc, PhD, FACC
Professor of Medicine and Cardiology at the Faculty of Health Sciences of the Simón Bolívar University
Research Director, Bios Foundation
Former President of the Colombian Society of Cardiology and Cardiovascular Surgery
Former president of the Colombian Heart Foundation
Former Governor of the Colombian Chapter of the American College of Cardiology
INTERASPIRE Colombia Deputy Coordinataor/Registry Nurse
Paula Luna
CSCCS Nurse
Specialist in epidemiology
Colombia INTERASPIRE Centres
Indonesia Heart Association 
Indonesian Heart Association President
Dr Isman Firdaus, SpJP(K), FIHA, FAPSIC, FAsCC, FESC, FSCAI
Critical Care and Interventional Cardiologist in National Cardiac Center Harapan Kita Hospital
Staff Physician of Cardiology and Vascular Medicine Department, Faculty of Medicine, University of Indonesia
INTERASPIRE National Coordinator
Dr Ade Meidian Ambari, SpJP(K), FIHA
Chairman of Prevention and Rehabilitation Division in National Cardiac Center Harapan Kita Hospital, Department of Cardiology, Faculty of medicine, University of Indonesia
Chairman of Working Group of Cardiovascular Prevention and Rehabilitation Indonesian Heart Association
Member of Working Group of Respiratory Care Indonesia
National Board of Exercise Is Medicine Indonesia Vice Secretary General Indonesian Heart Association
INTERASPIRE Sponsors
