INTERASPIRE - NIPC - National Institute for Prevention and Cardiovascular Health

An international Study of Cardiovascular Disease Prevention, Diabetes and Chronic Kidney Disease in partnership with the World Heart Federation, European Society of Cardiology, Asia Pacific Society of Cardiology, InterAmerican Society of Cardiology and Pan-African Society of Cardiology.

The objectives of this international study of 12,000 coronary patients across 30 countries from 5 WHO regions outside Europe are to (i) describe prevalence of cardiometabolic and renal risk factors in coronary patients; (ii) describe current risk factor management to defined targets by drug therapies (iii) provide an objective assessment of clinical implementation of international and national guidelines; (iv) investigate the reasons for variation in preventive cardiology practice between regions and countries; (v) promote the principles of best preventive cardiology practice through continental and national societies of cardiology and heart foundations.

INTERASPIRE includes in depth clinical and laboratory studies of (i) dysglycaemia and diabetes; (ii) chronic kidney disease; (iii) atrial fibrillation; (iv) familial hypercholesterolaemia; and (v) heart failure.

This international study is being conducted through National Societies of Cardiology which have responsibility for appointing National Coordinators, selecting geographical regions (minimum of three) and hospital centres (minimum of 6 in each country) together with Principal Investigators.

The study population is a consecutive sample of coronary patients from each hospital which meet the following diagnostic criteria: Acute coronary syndromes (acute myocardial infarction with ST elevation (STEMI) and Non ST elevation MI (Non-STEMI) and stable coronary artery disease). Patients are interviewed and examined in hospital using standardised methodology, including one central laboratory in Helsinki, Finland, for measurement of fasting lipids, glucose, HbA1c, creatinine and urinary albumin, and then followed up for hospitalisations, non-fatal and fatal cardiovascular events and all cause mortality.

A pilot study in Argentina (8 regions and 8 hospitals) and Malaysia (5 regions and 6 hospitals) is on-going and 400 coronary patient interviews from each country will be completed during 2019 -20; a total of 800 coronary patients. The main study was launched in 2020, starting with Colombia, followed by China, Indonesia, Japan, Kenya, Nigeria, Philippines, Singapore, Sudan, Tanzania, UAE and USA. With a minimum of 6 hospital centres in each country, we expect 400 coronary patient interviews in 2020-21 (200 in each of the African countries) ; a total of 4000 coronary patients.

The patient data from INTERASPIRE will be combined with the 8261 coronary patients from 27 countries from the WHO European region (EUROASPIRE V 2016-18) to give a complete real world picture of contemporary therapeutic management of cardiometabolic and renal disease and the impact such care has on event free survival.

Study design publication, Current Cardiology Reports, INTERASPIRE: an International Survey of Coronary Patients; Their Cardiometabolic, Renal and Biomarker Status; and the Quality of Preventive Care Delivered in All WHO Regions.

INTERASPIRE Co-Principal Investigators:

Prof David Wood,

MB ChB, MSc, FRCP, FRCPE, FFPHM, FESC, FACC, FAHA
Adjunct Professor of Preventive Cardiology
Director of Science, Strategy and International Relations
National Institute for Prevention and Cardiovascular Health
National University of Ireland – Galway
Emeritus Professor of Cardiology
Imperial College London
Past President World Heart Federation 2019-20

John William (Bill) McEvoy,

MB BCh BAO, MEd, MHS, FRCPI
Professor of Preventive Cardiology,
National University of Ireland, Galway Campus.
Medical and Research Director,
National Institute for Prevention and Cardiovascular Health
Consultant Cardiologist,
University College Hospital Galway, Saolta Healthcare Group.

INTERASPIRE Coordinating Centre, National Institute for Prevention and Cardiovascular Health, National University of Ireland Galway, Ireland

Agnieszka Adamska MBA, MSc

Research Project Manager,
National Institute for Prevention and Cardiovascular Health
Honorary Clinical Fellow School of Medicine,
National University of Ireland, Galway

Dr Catriona Jennings

Cardiovascular Specialist Research Nurse Coordinator

Prof Kornelia Kotseva

Senior Clinical Research Fellow and Consultant Cardiologist

INTERASPIRE Executive Committee

Co-Chairs:
Prof David Wood and Prof John William McEvoy

Prof Guy G. De Backer, MD, PhD

Honorary Professor, Ghent University
Faculty of Medicine and Health Sciences
Dept Public Health and Primary Care
University Hospital Ghent, Dept Cardiology
Belgium

Dr. Catriona Jennings PhD BA Hons PG Cert ULT RN FESC FPCNA

Cardiovascular Specialist Research Nurse Coordinator
National Institute for Prevention and Cardiovascular Health
National University of Ireland – Galway
Discipline of Medicine, Clinical Science Institute, Galway, Ireland

Professor Kornelia Kotseva, MD, PhD, FESC

Senior Clinical Research Fellow
National Institute for Prevention and Cardiovascular Health
National University of Ireland – Galway
Consultant Cardiologist
Imperial College Healthcare NHS Trust, London, UK

Prof. Dr. Dirk De Bacquer

Senior Full Professor of Epidemiology and Biostatistics
Head of the Epidemiology & Prevention Unit
Head of the Biostatistics Unit
Department of Public Health and Primary Care
Faculty of Medicine and Health Sciences
Ghent University – Belgium

Prof Lars Ryden

Senior Professor of Cardiology
FoU – Tema Hjärta och Kärl,
Karolinska Universitetssjukhuset/Solna
Sweden

Prof Gregory Y. H. Lip

Price-Evans Chair of Cardiovascular Medicine, University of Liverpool, UK;
Distinguished Professor, Aalborg University, Denmark

Prof Kosh Ray

Professor of Public Health and Consultant Cardiologist,
Imperial College London, UK

Iris Erlund, Research Manager

Biochemistry Laboratory
Forensic Toxicology Unit
Finnish Institute for Health and Welfare (THL), Helsinki, Finland

Academic Institutions partnering with INTERASPIRE

Data Management Centres:

EURObservational Research Programme (EORP), European Society of Cardiology, France
Céline Arsac, MSc., PMP – EORP Team Manager
Clara Berlé – Clinical Project Manager

AIMES Management Services Limited, Liverpool, UK
Richard Spragg – Technical Director
Shaun Atkinson – Data Manager

Statistical Centre – Faculty of Medicine and Health Sciences, Ghent University, Belgium
Professor Dirk De Bacquer

Central Laboratory – The National Institute for Health and Welfare (THL), Department of government Services, Forensic Toxicology Unit, Helsinki, Finland
Iris Erlund, Research Manager
Elina Jarvensivu – Interaspire Lead

Diabetes Centre – Cardiology Unit, Department of Medicine Solna, Karolinska Institutet Stockholm, Sweden
Professor Lars Ryden

Participating countries:

Malaysia

National Heart Association of Malaysia

National Heart Association of Malaysia President
Professor Wan Azman Wan Ahmad
FRCP, FAMM, FNHAM, FAPSC, FAsCC, FAPSIC, FSCAI, FACC, FESC, FASc
Senior Consultant Cardiologist
University Malaya Medical Centre, Kuala Lumpur, Malaysia

INTERASPIRE Malaysia National Coordinator
Associate Professor Ahmad Syadi Mahmood Zuhdi
University Malaya Medical Centre, Kuala Lumpur, Malaysia

INTERASPIRE Malaysia Deputy Coordinator
Dr Zainab Abu Kassim
University Malaya Medical Centre, Kuala Lumpur, Malaysia

Malaysia INTERASPIRE Centres

INTERASPIRE Malaysia Central Training, Kuala Lumpur, 10-11th Nov 2019

Argentina

Argentine Society of Cardiology

The Argentine Society of Cardiology President
Alejandro Rubén Hershson MD, MTSAC, FESC
Head of Outpatient Clinic and Cardiology Department – Institute of Cardiology and Cardiovascular Surgery – Hospital Universitario Fundación Favaloro. Associate Professor, Medicine Department, Favaloro Univeristy
Master in Management and Administration of Health Systems and Services, Favaloro University
Fellow of the European Society of Cardiology (FESC)
Full Member of the Argentine Society of Cardiology (MTSAC)

The Argentine Society of Cardiology Immediate Past President
Associate Professor Jose Luis Navarro Estrada, MD, MSc, MTSAC, FACC
Head of Coronary Unit – Hospital Italiano de Buenos Aires, Argentina
Vice Director Department of Research – Hospital Italiano de Buenos Aires
Staff Member, Senior Investigator
Master of Sciences (MSC)(UBA- Harvard)
Associate Professor of Medicine – Instituto Universitario del Hospital Italiano
Full Member of the Argentine Society of Cardiology

INTERASPIRE Argentine National Coordinator
Dr María Inés Sosa Liprandi, MTSAC-FACC
Coordinator Cardiovascular Research, Sanatorio Güemes, Buenos Aires , Argentina
Coordinator Heart Failure Unit, Sanatorio Güemes, Buenos Aires, Argentina
Medical Director, Idea Medica- Research&Education, Buenos Aires, Argentina
Director Cardiomyopathies Council Interamerican Society of Cardiology

INTERASPIRE Argentine Lead
Prof Alvaro Sosa Liprandi
Head of Cardiology, Sanatorio Güemes. Buenos Aires, Argentina
Director, Idea Médica. Research & Education
Director, Post Graduate Medical School in Cardiology, Universidad de Buenos Aires
President Elect. InterAmericanSociety of Cardiology

Argentina INTERASPIRE Centres

INTERASPIRE Argentina Central Training, Buenos Aires 6-7th March 2020

Colombia

Colombian Society of Cardiology and Cardiovascular Surgery

CSCCS President
Dr Fernán Del Cristo Mendoza Beltrán
Internal Medicine Specialist: Universidad de Cartagena – Colombia
Specialist in Adult Cardiology: Universidad El Bosque- Colombia
Critical Medicine and Intensive Care Specialist: Universidad de la Sabana – Colombia
Bioethics Specialist: Universidad Javeriana – Colombia
Specialist in Clinical Epidemiology: Universidad El Bosque – Colombia
Specialist in University Teaching: Universidad Militar Nueva Granada – Colombia
Head of the Department of Clinical Cardiology and Internal Medicine: Fundación Clínica Shaio
Head of the Heart Failure and Transplantation Unit: Fundación Clínica Shaio
Associate Professor and Director of the Postgraduate Program in Cardiology: Universidad El Bosque- Colombia
President of the Colombian Society of Cardiology and Cardiovascular Surgery
Fellow American College of Cardiology

CSCCS Immediate Past President :
Prof. Adalberto Quintero-Baiz MD, FACC
Professor of Cardiology at the Faculty of Health Sciences of the Simón Bolívar University
Medical Director, Cardiodiagnostico SA-Barranquilla
Research Subdirector, Bios Foundation
Past President of the Colombian Society of Cardiology and Cardiovascular Surgery

INTERASPIRE Colombia National Coordinator
Dr Miguel Urina Triana MD, Msc, PhD, FACC
Professor of Medicine and Cardiology at the Faculty of Health Sciences of the Simón Bolívar University
Research Director, Bios Foundation
Former President of the Colombian Society of Cardiology and Cardiovascular Surgery
Former president of the Colombian Heart Foundation
Former Governor of the Colombian Chapter of the American College of Cardiology

INTERASPIRE Colombia Deputy Coordinataor/Registry Nurse
Paula Luna
CSCCS Nurse
Specialist in epidemiology

Colombia INTERASPIRE Centres

INTERASPIRE Colombia Virtual Training, Bogota/London 11th July 2020

Indonesia

Indonesia Heart Association

Indonesian Heart Association President
Dr Isman Firdaus, SpJP(K), FIHA, FAPSIC, FAsCC, FESC, FSCAI
Critical Care and Interventional Cardiologist in National Cardiac Center Harapan Kita Hospital
Staff Physician of Cardiology and Vascular Medicine Department, Faculty of Medicine, University of Indonesia

INTERASPIRE National Coordinator
Dr Ade Meidian Ambari, SpJP(K), FIHA
Chairman of Prevention and Rehabilitation Division in National Cardiac Center Harapan Kita Hospital, Department of Cardiology, Faculty of medicine, University of Indonesia
Chairman of Working Group of Cardiovascular Prevention and Rehabilitation Indonesian Heart Association
Member of Working Group of Respiratory Care Indonesia
National Board of Exercise Is Medicine Indonesia Vice Secretary General Indonesian Heart Association

Indonesia INTERASPIRE Centres

Indonesia Group

Philippines

Philippines Heart Association

Philippine Heart Association President
Dr Orlando R. Bugarin, MD, FPCP, FPCC
Adult Cardiologist
Past President, Bataan Medical Society Chairman of Working Group of Cardiovascular Prevention and Rehabilitation Indonesian Heart Association
Advisor, CPR-Ready Philippines Campaign
Past Chair, PHA Council on Cardiopulmonary

Administrator – Hospital Operations Personnel and Support Services, Centro Medico De Santisimo Rosario (Bataan)

Philippine Heart Association Immediate Past President
Prof Aurelia G. Leus, MD, FPPS, FPCC
PHA Immediate Past Present and Governor, ACC Chapter Philippines 2020-2021
Pediatric/Interventional Cardiologist
Past President, Philippine Society if Pediatric Cardiology
Past President, Philippine Society of Cardiac Catheterization and Interventions Affiliated with Makati Medical Center

INTERASPIRE Philippines National Coordinator
Dr Rodney M. Jimenez, MD, FPCP, FPCC
PHA Director and Chair of the PHA Continuing Education Program Committee
Adult/Interventional Cardiologist
Asst. Professor, College of Medicine, University of the East Ramon Magsaysay Memorial Medical Center, Inc.
Training Officer, Adult Cardiology Fellowship Training, St. Luke’s Medical Center (SLMC) – Global City Training Officer for the Clinical Research Fellowship of the Cardiac Catheterization Laboratory of SLMC BGC and SLMC Quezon City

INTERASPIRE Philippines Deputy Coordinator
Grace Mendoza
Philippine Clinical Research Professionals

Philippines INTERASPIRE Centres

INTERASPIRE Philippines Virtual Training 15.04.21

Singapore

Singapore Heart Foundation/National University Heart Centre, Singapore

Singapore Heart Foundation Chairman
Dr Tan Huay Cheem
Senior Consultant, Department of Cardiology, National University Heart Centre, Singapore
Professor of Medicine, Yong Loo Lin School of Medicine, national University of Singapore
Chairman of Singapore Heart Foundation

INTERASPIRE Singapore National Coordinator
A/Prof Jack Tan Wei Chieh
Deputy Head of NHCS and Senior Consultant, Department of Cardiology
Head of Cardiology Seng Kang Hospital
President Asian Pacific Society of Cardiology
President International Society of Pharmacotherapy

INTERASPIRE Singapore Principal Investigator
Dr Yeo Tee Joo
Consultant, Department if Cardiology, National University Heart Centre, Singapore
Director, Cardiac Rehabilitation, Department of Cardiology, national University Heart Centre, Singapore
Assistant Professor, Yong Loo Lin School of Medicine, National University of Singapore

INTERASPIRE Deputy Research Coordinator
Cher Yi Wong

Clinical Research Coordinator
National University Heart Centre, Singapore